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Peruvian Journal of Neurosurgery

Spinal Metastases of Hepatocellular Carcinoma in Patient with Suspected Recurrence of Spinal Tumor

Jerson Flores C. MD, Relix Huamán H. MD, William Anicama L. MD
Abstract (Spanish) || Full Text || PDF (Spanish)

ABSTRACT

 

Spinal metastasis from hepatocellular carcinoma is an uncommon but serious disorder, occurring in 1.2 to 3% of patients with hepatocellular carcinoma, which is a common malignancy in developing countries and although its extrahepatic spread is common especially to lung and lymph nodes, spinal metastasis is rare and only few reports have been described in the past. The diagnosis of metastasis is made by needle biopsy in the presence of symptoms in a patient with infiltrative lesions of dorsallumbar spine and severe affectation of general condition. The treatment of spinal metastases of hepatocellular carcinoma by surgery is controversial because their appearance usually denotes the terminal state of patients many of whom are not candidates for surgery. The most widely accepted treatment option is radiation therapy, which has proved effective and safe with good symptomatic response and local control. Early diagnosis is essential for the immediate starting of radiotherapy because a positive response to radiotherapy can improve the quality of life of patients and potentially survival. We present a patient with spinal metastasis of hepatocellular carcinoma previously operated of filum terminal schwannoma.
     KeyWords: Hepatocellular carcinoma; Spinal metastasis; Radiotherapy