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Peruvian Journal of Neurosurgery
Clinical practice guide of Myelomeningocele
Sociedad Peruana de Neurocirugía
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ABSTRACT
Myelomeningocele, an open defect of the neural tube, is the most common congenital anomaly of the central nervous system (CNS) and the main cause that determines a number of growth and developmental disabilities in the affected child. It occurs due to a failure of the closure of neurulation in the caudal neural plate during the fourth week of gestation (22 to 26 days of gestation). It is characterized by dorsal protrusion of the meninges through a bony defect at the level of the spinal midline, without a dermal covering, forming a sac containing cerebrospinal fluid (CSF) and neural tissue Dysplastic, and which is usually associated with paralysis of the spinal nerves.